Plinest in Korea: Is Rejuran the Closest Korean Alternative?

Looking for Plinest in Korea?

Patients who have received Plinest in Italy, the United Kingdom, or elsewhere in Europe often ask whether they can continue the same treatment while visiting Seoul.

Plinest does not currently have approval from Korea’s Ministry of Food and Drug Safety, so it is not available as an approved treatment at Korean dermatology clinics.

The closest option to discuss is usually Rejuran, one of Korea’s best-known PN skin boosters. Rejuran is not the same product as Plinest, but the two treatments have several important similarities.

Recently, more patients have been asking whether they can receive Plinest while traveling in Korea, especially in Seoul or Gangnam.

However, Plinest is not currently approved by Korea’s Ministry of Food and Drug Safety, so it is not a treatment that can be performed at Korean dermatology clinics.

Then what would be the closest option? The first product many people compare it with is Rejuran, one of Korea’s best-known PN skin boosters.

What Is Plinest?

Plinest is a PN skin booster made by the Italian company Mastelli. In Europe, it is used to improve skin texture, fine lines, dryness and elasticity on areas such as the face, neck and décolleté.

Standard Plinest contains 40mg of PN-HPT in a 2mL syringe, giving it a concentration of 20mg/mL.

Unlike a dermal filler, Plinest is not mainly used to add volume or change facial contours. Its purpose is to support gradual improvements in overall skin quality.

Plinest may be injected through multiple microdroplets. Linear injection and cannula techniques are also used, depending on the treatment area and the practitioner’s approach.

Plinest vs Rejuran: What Do They Have in Common?

Rejuran is a Korean injectable treatment made with salmon-derived polynucleotides. Standard Rejuran is also commonly described as containing PN at a concentration of 20mg/mL.

This means that standard Plinest and standard Rejuran have the same stated PN concentration.

Both treatments are commonly considered for concerns such as:

• Fine lines

• Dry or rough skin

• Loss of elasticity

• Uneven skin texture

• Enlarged-looking pores

• Skin that feels thinner with age

Neither treatment is designed to create the immediate volume associated with dermal fillers. Changes in skin texture and firmness tend to appear more gradually.

Plinest and Rejuran Are Not Identical

Although the stated PN concentration is similar, Plinest and Rejuran are not interchangeable products.

They are made by different manufacturers using different purification and production technologies. Their viscosity, physical properties and behaviour after injection may also differ.

The injection techniques commonly associated with each product are different as well.

In Europe, Plinest may be injected with microdroplets, linear threads or a cannula to distribute the product across a wider area.

In Korea, Rejuran is best known for the micro-papule or serial puncture technique. This involves placing small amounts of product at multiple points in the skin. The temporary raised bumps created by this method are often called “embossing” in Korea.

However, not every Rejuran treatment needs to be performed in exactly the same way. Injection depth, spacing and technique can be adjusted according to skin thickness, treatment area and the patient’s main concerns.

Which Rejuran Is Closest to Plinest?

For someone who previously received standard Plinest across the full face, standard Rejuran would usually be the first product to discuss during a consultation in Korea.

The two products share a similar PN concentration and are used for broadly similar concerns, including fine lines, skin texture and elasticity.

Still, patients should not expect Rejuran to feel exactly like Plinest or produce an identical result. It is better understood as a Korean PN treatment with similar goals.

Other Rejuran products may be more suitable for specific concerns.

Rejuran i

Rejuran i is commonly considered for delicate areas such as the skin around the eyes. It may be discussed when under-eye texture or fine lines are the main concern.

Rejuran HB Plus

Rejuran HB Plus contains PN together with hyaluronic acid and lidocaine. It may be considered for patients who are concerned about dryness or discomfort during injection.

Its formula is different from standard Plinest, which is a PN-based product without the same combination of ingredients.

Rejuran S

Rejuran S is usually considered for more localised concerns, including selected acne scars or depressed areas. It serves a different purpose from a full-face Plinest treatment.

Can Rejuran Deliver Similar Results?

Rejuran is not an exact replacement for Plinest. However, it is one of the closest Korean alternatives for patients seeking a PN skin booster in Seoul.

Both treatments aim to improve skin quality without dramatically changing facial shape or volume.

Patients usually choose PN treatments for gradual improvement in:

• Skin texture

• Fine lines

• Hydration

• Elasticity

• Overall skin condition

The small bumps or swelling visible immediately after treatment should not be confused with the final result. These usually settle first, while changes in skin quality appear more gradually.

PN treatments are also often performed as a series rather than as a single session. The recommended number of sessions and treatment interval should depend on skin condition, treatment area and previous procedure history.

What to Check Before Getting Rejuran in Korea

When comparing Rejuran treatments at a Korean dermatology clinic or Gangnam skin clinic, price should not be the only consideration.

Patients should ask:

• Which Rejuran product will be used

• How many millilitres will be injected

• Whether an authentic product will be opened for the treatment

• Which areas will be treated

• What injection technique will be used

• How much downtime to expect

The skin around the eyes, cheeks and mouth does not have the same thickness. Injection depth and dose should therefore be adjusted by area rather than applied in exactly the same way across the entire face.

Patients who previously received Plinest through a cannula should mention this during their consultation. It helps the doctor understand their previous experience and discuss whether a needle, injector, cannula or combined technique would be more appropriate.

Looking for Plinest in Korea? Rejuran Is the Closest Comparison

Plinest is not currently approved for use in Korea, so patients should not expect to find it as an approved treatment at Korean dermatology clinics.

For those looking for a similar PN skin booster in Korea, Rejuran is the most relevant product to compare.

Standard Plinest and standard Rejuran both have a stated PN concentration of 20mg/mL and are used for similar concerns, including fine lines, skin texture and elasticity. However, their manufacturing technologies, physical properties and commonly used injection techniques are not the same.

Rejuran should therefore be viewed not as an identical replacement for Plinest, but as the closest Korean PN alternative for patients seeking a similar approach to skin quality improvement.

The product name matters, but so do the doctor’s injection technique, the treatment depth, the amount used and whether the treatment plan is suited to the patient’s skin.

Source: UH CELL Clinic Gangnam Medical Director Kim Yeonjin

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